Pathogens… Just the word causes worry amongst
anybody who knows what they are. And in quick, they’re one thing we all want to
steer clear of. We not too long ago got the likelihood to speak with Milan Patel, Co-founder and CEO
of PathogenDx, a Scottsdale, AZ primarily based firm which has created a disruptive
technologies: DNA-primarily based testing for cannabis as effectively as other industries.
Verify out the interview under to study a lot more
about this technologies and what it suggests for cannabis growers and shoppers.
CM: What is
PathogenDx – in one particular sentence, and then in depth? What is the technologies in
play right here?
Patel: In one particular sentence, PathogenDx is an Arizona biotechnology
firm that has created a disruptive DNA-primarily based technologies to test for
various pathogens (bacterial and fungal organisms that trigger contamination) in
a fraction of the time, price and labor to guarantee cannabis, hemp, meals, ag, and
water is protected for consumption.
The globe is filled with
damaging pathogens that increasingly threaten the security of our cannabis, hemp,
meals and water provide. And however, testing labs nonetheless rely on the Petri dishes scientists
invented more than a century ago. At PathogenDx, microbial testing has now been
brought into the contemporary age. The company’s patent-winning scientists have
invented a game-altering DNA-primarily based microarray technologies (see image under) that
accelerates the testing identification and quantification of microbes (from
E-coli to powdery mildew)—delivering precise outcomes in just six hours without having
the want for enrichment or DNA purification. The firm entered the Cannabis
industry to demonstrate the energy of the Ultra-speedy DNA microarray to prove the
capability of delivering the quickest microbial test in the cannabis sector
although meeting the security testing regulations.
CM: The significant
tool in testing has often been the Petri dish – why adjust that now? How does DNA
come into play?
Patel: The Petri dish has been about for 140 years. Even so, testing outcomes
take rather lengthy due to the fact with a Petri dish, you have to take a sample, enrich
any bacterial or fungal organisms in that sample, streak it on an agar culture
and wait for the cells of the bacterial or fungal pathogens to develop just before you
get a outcome. This can take anyplace from three days up to 7 days. When you have a
lot of samples coming into a lab, it can be really unwieldy.
Why adjust now? – The provide chain of
cannabis, hemp, meals, agriculture and water is a lot more effective now, and with the
item moving by means of the provide chain substantially quicker to the finish client, the
danger is greater due to the fact a possible contaminated meals is most likely to get consumed
just before outcomes are obtained from petri dish testing. This is evident by the
continued increases in meals borne outbreaks in the final two-three decades, and current
examples are the meals borne outbreaks at Chipotle and the Romaine lettuce
incident. Fundamentally a 19th century option can not meet the requires
and demands of these markets, and a 21st century option is required
whereby outcomes are delivered quicker just before contaminated finish item gets
How does DNA come into play? – DNA comes
into play due to the fact the methodology by which the method operates is unique in
that it is a targeted strategy: you do not have to wait for the actual pathogen
cells to develop, you are capable to recognize that the item is contaminated at the
molecular level, and you can get a outcome in hours.
Patel: The largest threats facing farmers and their cannabis/hemp crops is
continual contamination inside grows with a higher level of presence of each
bacterial and fungal microbes in the finish sample. In addition, we are beginning
to see enhanced presence of viruses – specially for hemp farmers – which is
wreaking havoc as petri dish testing can not test for viruses. This outcomes in
catastrophic losses each from an financial standpoint, as effectively as yield
CM: Even although
PathogenDx was created for hemp and cannabis, you say it can be utilized to
test other agricultural crops, water, even meat and dairy places. Will the very same
test and process be utilized for unique factors what else does PathogenDx want
to do to enter the Meals and Dairy sphere?
Patel: We have produced the technologies universally applicable to various markets
as effectively as ubiquitous, in that at the base level, it is one particular method. Irrespective of whether
you are testing cannabis, romaine, milk, water or something else, the method is
proficiently the very same. The content material of the kits are mainly the very same, but
occasionally enhanced with unique bacterial or fungal organisms that are
distinct to that market.
at present submitting the use of the technologies as a certified process to the
AOAC for meals and environmental testing at the federal level. We count on to have
certification by mid-2020, and after that takes place, PathogenDx will have access
to a $30B industry. In addition, we are creating a test that can test up to 20
pathogens that are at present causing high-quality problems in the milk and dairy
market. We strategy to introduce a item in 2020 for this industry.
CM: What’s subsequent
for PathogenDx in 2020? Exactly where else do you see application of this technologies?
Patel: We are expanding the applications of the technologies into the Meals,
Environmental, Dairy markets, as effectively as introducing a plant pathogen kit that
will broaden the testing capability in cannabis, hemp and Agriculture. The technologies has possible into the substantially bigger clinical
diagnostics with a multitude of clinical applications. At the present time, the
firm is operating with various collaborators to evaluate important industry