Girls all over the world have been on the lookout for a extra pure answer to managing the signs of menopause. One such prospect might be CBD, largely as a consequence of its affect on the endocannabinoid system (ECS). Earlier than we check out the connection between the ECS and menopause, let’s first perceive what causes menopause.
Menopause signifies a shift in a girl’s ranges of oestrogen and progesterone. Consequently, intervals will cease, and getting pregnant naturally is not an possibility. Don’t fear although, it is a pure a part of getting older, and one thing each girl goes by. The issue with menopause is that, whereas it could be a pure course of, that doesn’t make the signs any extra snug to dwell with. For some ladies, sizzling flashes, evening sweats, issue sleeping, low temper, and ache throughout intercourse can final for as much as fourteen years.
Standard remedies for signs of menopause embody hormone substitute remedy (HRT), counselling, and changes to eating regimen or train regime. The issue is that as a result of signs persist for years, treatment like HRT can take its toll on the physique and inflict a number of uncomfortable side effects.
Residing with menopause signs
Sometimes, menopause impacts ladies aged 45–55, however it might happen earlier or later than this timeframe. As we talked about above, menopause is caused by a change within the physique’s hormone ranges. From the mid-thirties, a girl’s oestrogen ranges begin to decline, signifying the beginning of perimenopause. The regular decline in oestrogen is what results in lots of the signs related to menopause. Signs can proceed previous menopause into the postmenopausal interval, however they’re normally much less extreme than throughout perimenopause.
Simply by itemizing the signs of menopause, it’s simple to see the big affect on a girl’s high quality of life. Many people are grouchy or really feel down after one evening of dangerous sleep, however think about the identical points persisting for years. Scorching flashes can come on the worst time, making it troublesome to pay attention, and painful intercourse places a pressure on any relationship. Over the centuries, ladies have simply needed to grin and bear the signs of menopause, however due to ongoing analysis, CBD could be the pure answer to creating signs simpler to dwell with.
CBD’s affect on the endocannabinoid system may play a key position
CBD is believed to be helpful due to the interactions it has with the ECS and its activation of sure enzymes and receptors. It doesn’t sort out menopause immediately, however as a substitute could affect a number of menopausal signs.
The extraordinarily widespread “sizzling flashes” skilled throughout menopause characterize the physique’s incapability to control temperature accurately. Beforehand, research have proven that the endocannabinoid anandamide (AEA) could play an element in our mind’s skill to control temperature. Sadly, AEA is shortly damaged down within the physique by an enzyme referred to as FAAH. CBD, nevertheless, has been proven to dam the manufacturing of FAAH, permitting enhanced signalling of anandamide.
A lack of bone density is one other symptom of menopause, which, if left unchecked, can result in osteoporosis. This time, a examine revealed on ScienceDirect outlined a relationship between CB receptors and TRPV1 channels. They discovered that sufferers with osteoporosis had elevated TRPV1 channel expression, which ends up in “large overexpression of CB2 receptors”. Their findings not solely confirmed the position of the endocannabinoid system in osteoporosis, however they level to a possible remedy with CBD. A supporting examine discovered that CBD “is reported to be most potent at influencing TRPV1 and TRPM8 channels. By regulating TRPV channels utilizing CBD, it’s doable that the overexpression present in osteoporosis sufferers might be decreased, and new therapies launched consequently”.
The way forward for CBD and menopause
Invoking the research listed above, and CBD’s proposed anxiolytic results, it’s comprehensible why the compound is being explored as a therapeutic remedy for the signs of menopause. CBD could possibly help the physique on a number of fronts—due to its interplay with the ECS—with a fraction of the uncomfortable side effects related to HRT drugs. Contemplating menopause is a pure a part of getting older, it is smart that future remedies look to pure options.