The Endocannabinoid Technique and Worry-Linked Memories

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Researchers, out of the Emory University College of Medicine, publishing a study in Neuropsychopharmacology, have located that growing or decreasing the body’s endocannabinoid levels has substantial impacts on eliminating worry-related memories. Endocannabinoids are the body’s naturally-made cannabinoids and have been strongly linked to regulating the body’s worry responses.

In this study, it was demonstrated in mice models that disrupting the endocannabinoid method by blocking cannabinoid receptors improved the retention of memories related with worry. On the other hand, it was shown that growing the body’s endocannabinoid levels by stopping their breakdown decreased the retention of worry-related memories. Moreover, mice with improved endocannabinoid levels have been much less probably to have worry-responses return when researchers attempted to reinstate them.

These benefits have profound implications for the therapy and even the prevention of Post-Traumatic Strain Disorder, or PTSD. The disorder is generally treated with anti-depressants, but these drugs treat the symptoms of PTSD rather than its causes. If this study’s benefits hold correct, the body’s endocannabinoid method could be the 1st line of defense against creating PTSD. CBD is believed to possibly boost the naturally-made endocannabinoid levels[1], suggesting it could play a essential function in treating and stopping PTSD by lowering the retention of worry-related memories.

The article’s abstract can be located right here.

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[1] Ujváry I, Hanus L (2014). “Human metabolites of cannabidiol: a critique on their formation, biological activity, and relevance in therapy”. Cannabis and Cannabinoid Investigation. 1 (1): 90–101.

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