In a new study from the University College London (UCL), a group of researchers focused on the distinction in between consuming cannabis strains that have higher levels of THC, and strains that have important quantities of each THC and CBD.
The precise effects on the brain have been monitored by an fMRI (functional magnetic resonance imaging), which measures alterations in blood flow and neural activity.
Brain scans of the 17 participants showed that the higher-THC strain impaired the functionality of the default mode network, specially in the posterior cingulate region.
The dysfunctionality of the posterior cingulate region closely corresponded with the sensation of “becoming higher”, displaying that the effects of THC on this section are connected with the cerebral intoxication of cannabis.
The higher-THC strain also brought on disruption to the salience network, which determines what sensory or emotional details we concentrate on at a provided time.
Improper functioning of the salience network was currently connected with psychosis and addiction prior to this study.
In contrast to the strain which only contained higher levels of THC, the strain that also had higher levels of CBD brought on minimal disturbances to these regions of the brain.
The outcomes of this study help the theory that the CBD cannabinoid (when utilized in mixture with THC) diminishes the unfavorable effects of THC, like the psychoactivity brought on by tetrahydrocannabinol, though adding to the medicinally effective effects.
Dr. Matt Wall (the major author of the study), comments:
“Over the final two decades, prices of addiction and psychosis linked to cannabis have been on the rise, though at the identical time stronger strains of cannabis with extra THC and much less CBD have turn out to be increasingly popular.
“We have now identified that CBD seems to buffer the user against some of the acute effects of THC on the brain.”